Corpus ID: 23166277

[Mechanism and action characteristics studies of a quinoxalinone compound against HIV-1 replication].

@article{Ba2013MechanismAA,
  title={[Mechanism and action characteristics studies of a quinoxalinone compound against HIV-1 replication].},
  author={Ming-Yu Ba and Y. Cao and B. Xu and Y. Guo},
  journal={Yao xue xue bao = Acta pharmaceutica Sinica},
  year={2013},
  volume={48 6},
  pages={
          860-5
        }
}
  • Ming-Yu Ba, Y. Cao, +1 author Y. Guo
  • Published 2013
  • Chemistry, Medicine
  • Yao xue xue bao = Acta pharmaceutica Sinica
  • This study is to investigate the mechanism and action characteristics of 6-chloro-3-methyl-4-(2-methyoxycarbonylthiophene-3-sulfonyl)-3, 4-dihydroquinoxa-lin-2-(1 H)-one (XU07011) against HIV-1 replication. XU07011 anti-HIV activity was tested by using VSVG/HIV pseudotype viral system and confirmed by HIV-1 live viruses' infectious assay. Time of addition was used to test HIV-1 reverse transcription process. RNA-dependent DNA polymerase activity and RNase H activity were tested by using enzyme… CONTINUE READING

    References

    SHOWING 1-10 OF 16 REFERENCES
    [Screening of HIV-1 replication inhibitors by using pseudotyped virus system].
    • Y. Cao, Y. Guo
    • Biology, Medicine
    • Yao xue xue bao = Acta pharmaceutica Sinica
    • 2008
    • 8
    HIV-1 antiretroviral drug therapy.
    • 552
    • PDF
    Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand.
    • 2,733
    • PDF