[Mdr-1 ribozyme in the reversal of multidrug resistance in human ovarian cancer].

@article{Yang2003Mdr1RI,
  title={[Mdr-1 ribozyme in the reversal of multidrug resistance in human ovarian cancer].},
  author={Xiao-kui Yang and Hui Jun Xing and Qing-lei Gao and Wei Wang and Su-fang Wu and Yun-ping Lu and Shixuan Wang and Ding Ma},
  journal={Zhonghua zhong liu za zhi [Chinese journal of oncology]},
  year={2003},
  volume={25 5},
  pages={425-8}
}
OBJECTIVE To study the mechanism of multidrug resistance and its reversal by mdr-1 ribozyme in human ovarian cancer. METHODS The expression of mdr-1 and p-glycoprotein (p-gp) was studied by confocal laser microscope (Confocal), RT-PCR and Western blot analysis in adriamycin-resistant human ovarian cancer cell line (A2780/ADM) and adriamycin-sensitive one… CONTINUE READING