Corpus ID: 44358017

[Management of osteoarthritis: oral therapies].

@article{Richette2012ManagementOO,
  title={[Management of osteoarthritis: oral therapies].},
  author={Pascal Richette},
  journal={La Revue du praticien},
  year={2012},
  volume={62 5},
  pages={
          654-60
        }
}
  • P. Richette
  • Published 1 May 2012
  • Medicine
  • La Revue du praticien
According to the European League of Associations of Rheumatology (EULAR) and the American College of Rheumatology (ACR), acetaminophen should be used as a first-line therapy in patients with osteoarthritis, because of its safety and effectiveness. NSAID should be considered in patients unresponsive to acetaminophen, and should be prescribed at the lowest effective dose and for the shortest duration. The use of stronger analgesics, such as weak opioids and narcotic analgesics, is only indicated… Expand
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12 Citations
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12 Citations

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Citation Type

Safety and efficacy of paracetamol and NSAIDs in osteoarthritis: which drug to recommend?
TLDR
Given the putative gastrointestinal and cardiovascular toxicity and poor analgesic properties of acetaminophen in OA, its use in patients with risk factors is questionable and the choice of NSAIDs, traditional or coxibs, should be based on individual patient risk factors. Expand
Management of Osteoarthritis with Avocado/Soybean Unsaponifiables
Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activities of millions of Americans, and it is one of the most common causes of disability in the world. With… Expand
Effects of Arthro-7 ® in relieving symptoms of osteoarthritis with mild to moderate arthralgia
TLDR
Arthro-7 has shown potent effects in improving and relieving osteoarthritis-related symptoms, particularly joint pain, anchylosis, and difficulty going down stairs. Expand
Effects of Arthro-7 ® in relieving symptoms of osteoarthritis with mild to moderate arthralgia [Corrigendum]
TLDR
Arthro-7 has shown potent effects in improving and relieving osteoarthritis-related symptoms, particularly joint pain, anchylosis, and difficulty going down stairs. Expand
Chondroitin sulphate: a focus on osteoarthritis
TLDR
This review highlights the potential of CS, either alone or in combination with other drugs, to attract the scientists engaged in OA treatment and management across the world. Expand
Long-term acetaminophen treatment induced liver fibrosis in mice and the involvement of Egr-1.
TLDR
Long-term administration of APAP induced liver fibrosis in mice, and Egr-1 was critically involved in this process, and a warning and reference is pointed out for patients with long-term APAP ingestion in clinic. Expand
Arthrocen, an avocado-soy unsaponifiable agent, improves acetic acid-induced colitis in rat by inhibition of NF-kB signaling pathway.
TLDR
It is demonstrated that Arthrocen reduced macroscopic and microscopic damage compared to the acetic acid group, and decreased the activity of MPO and TNF-α as well as the protein expression of pNF-kB in rat colon tissue. Expand
Primäre versus sekundäre Omarthrose – Diagnostik und Therapie
Bei der Omarthrose handelt es sich - analog zur sogenannten Periarthritis humeroscapularis- um kein homogenes Krankheitsbild. Anamnese, Klinik und radiologische Darstellung von primaren und… Expand
Natural product andrographolide alleviated APAP-induced liver fibrosis by activating Nrf2 antioxidant pathway.
TLDR
Nrf2 is critically involved in preventing liver fibrosis induced by long-term administration of APAP in mice, and Andro alleviates APAP-induced Liver fibrosis by attenuating liver oxidative stress injury via inducing Nrf2 activation. Expand
Omarthrose primitive versus omarthrose secondaire – diagnostic et traitement
Comme la periarthrite scapulohumerale, l’omarthrose ne correspond pas a un tableau clinique homogene. L’anamnese ainsi que la presentation clinique et radiologique des formes primitives et… Expand
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