[Management of osteoarthritis: oral therapies].
@article{Richette2012ManagementOO, title={[Management of osteoarthritis: oral therapies].}, author={Pascal Richette}, journal={La Revue du praticien}, year={2012}, volume={62 5}, pages={ 654-60 } }
According to the European League of Associations of Rheumatology (EULAR) and the American College of Rheumatology (ACR), acetaminophen should be used as a first-line therapy in patients with osteoarthritis, because of its safety and effectiveness. NSAID should be considered in patients unresponsive to acetaminophen, and should be prescribed at the lowest effective dose and for the shortest duration. The use of stronger analgesics, such as weak opioids and narcotic analgesics, is only indicated…
11 Citations
Safety and efficacy of paracetamol and NSAIDs in osteoarthritis: which drug to recommend?
- MedicineExpert opinion on drug safety
- 2015
Given the putative gastrointestinal and cardiovascular toxicity and poor analgesic properties of acetaminophen in OA, its use in patients with risk factors is questionable and the choice of NSAIDs, traditional or coxibs, should be based on individual patient risk factors.
Management of Osteoarthritis with Avocado/Soybean Unsaponifiables
- Medicine, BiologyCartilage
- 2015
Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activities of millions of Americans, and it is one of the most common causes of disability in the world. With…
Effects of Arthro-7 ® in relieving symptoms of osteoarthritis with mild to moderate arthralgia [Corrigendum]
- Medicine
- 2013
Arthro-7 has shown potent effects in improving and relieving osteoarthritis-related symptoms, particularly joint pain, anchylosis, and difficulty going down stairs.
Long-term acetaminophen treatment induced liver fibrosis in mice and the involvement of Egr-1.
- Biology, MedicineToxicology
- 2017
Arthrocen, an avocado-soy unsaponifiable agent, improves acetic acid-induced colitis in rat by inhibition of NF-kB signaling pathway.
- MedicineJournal of food biochemistry
- 2020
It is demonstrated that Arthrocen reduced macroscopic and microscopic damage compared to the acetic acid group, and decreased the activity of MPO and TNF-α as well as the protein expression of pNF-kB in rat colon tissue.
Current World Literature
- Computer ScienceCurrent opinion in rheumatology
- 2013
Current development in genomic and proteomic research for asthma, and potential implications for ethical, legal, and social implications of genomic medicine, are studied.
Natural product andrographolide alleviated APAP-induced liver fibrosis by activating Nrf2 antioxidant pathway.
- Medicine, BiologyToxicology
- 2018
Omarthrose primitive versus omarthrose secondaire – diagnostic et traitement
- 2013
Comme la periarthrite scapulohumerale, l’omarthrose ne correspond pas a un tableau clinique homogene. L’anamnese ainsi que la presentation clinique et radiologique des formes primitives et…
Controlled-release triple anti-inflammatory therapy based on novel gastroretentive sponges: characterization and magnetic resonance imaging in healthy volunteers.
- Materials ScienceInternational journal of pharmaceutics
- 2014
Chondroitin sulphate: a focus on osteoarthritis
- Biology, MedicineGlycoconjugate Journal
- 2016
This review highlights the potential of CS, either alone or in combination with other drugs, to attract the scientists engaged in OA treatment and management across the world.