[Male pseudohermaphroditism caused by 17-alpha-hydroxylase deficiency. Personal case reports and a review of the literature].

@article{Marinis1989MalePC,
  title={[Male pseudohermaphroditism caused by 17-alpha-hydroxylase deficiency. Personal case reports and a review of the literature].},
  author={Laura de Marinis and Antonio Mancini and A Saporosi and Francesco Calabr{\`o} and Michele Massari and E. Moneta and Edoardo Menini and Alessandro Barbarino},
  journal={Minerva ginecologica},
  year={1989},
  volume={41 7},
  pages={337-42}
}
Adrenal hyperplasia due to 17-alpha-hydroxylase deficiency is coupled with precocious hypogonadism, which causes pseudohermaphroditism in XY subjects and primary amenorrhea in XX subjects. The physiology of gluco- and mineral-corticoid adrenal activity, as well as the biosynthesis of gonadal steroids, is totally altered. We report two cases of XY subjects, identified as females, who came to our observation for primary amenorrhea and exhibited a hypertension with hypokaliemia. We also report a… CONTINUE READING