[Loss of heterozygosity of chromosome 1p/19q and p53 protein expression in oligodendroglioma].

OBJECTIVE To study the status of loss of heterozygosity (LOH) of chromosome 1p/19q and p53 protein expression in oligodendroglioma, as compared to astrocytoma. METHODS One hundred and ninety-one cases of glioma of different histologic types and grades, including 116 cases of low-grade of oligodendroglioma (86 paraffin-embedded and 30 fresh tissues), 45… CONTINUE READING