[Local anesthesia after percutaneous application. II].

  title={[Local anesthesia after percutaneous application. II].},
  author={J Ziegenmeyer and Nicholas F Reuter and Frangois Meyer},
  journal={Archives internationales de pharmacodynamie et de therapie},
  volume={224 2},
Cyclohexane and hexadecane have been found to accelerate the penetration of local anesthetics (lidocaine, fomocaine, procaine) through the intact skin of guinea-pigs. Dissolved in cyclohexane, the potency of lidocaine is twice that of fomocaine, the latter being more active than procaine. When dissolved in hexadecane, the activity of the local anesthetics… CONTINUE READING