[Liver stiffness measurement for the diagnosis of hepatic fibrosis in patients with chronic viral hepatitis].

@article{Kang2007LiverSM,
  title={[Liver stiffness measurement for the diagnosis of hepatic fibrosis in patients with chronic viral hepatitis].},
  author={Joon Koo Kang and Jae Youn Cheong and Sung Won Cho and Jin Hui Cho and Jin Sun Park and Yeong Bae Kim and Dong Joon Kim and Seong Gyu Hwang and Jin Mo Yang and Young Nyun Park},
  journal={The Korean journal of hepatology},
  year={2007},
  volume={13 4},
  pages={
          521-9
        }
}
BACKGROUND AND AIMS FibroScan is a new medical device that noninvasively measures liver stiffness. The aim of this study was to assess the accuracy of the liver stiffness measurement by FibroScan for making the diagnosis of liver fibrosis in patients with chronic viral hepatitis. METHODS We studied 103 patients with chronic viral hepatitis B or C and they underwent FibroScan and liver biopsy between October 2005 and August 2006. Liver fibrosis was staged on a 0-4 scale according to the Korean… 
[The usefulness of transient elastography to diagnose cirrhosis in patients with alcoholic liver disease].
TLDR
Transient elastography is a useful method for diagnosing cirrhosis in patients with alcoholic liver disease and it is found that liver stiffness differed significantly between each fibrosis stage.
[Factors associated with liver stiffness in chronic liver disease].
TLDR
Liver stiffness as measured by transient elastography is associated with the grade of necroinflammatory activity and the stage of fibrosis, irrespective of serum ALT levels.
[Clinical factors influencing liver stiffness as measured by transient elastography (Fibroscan) in patients with chronic liver disease].
TLDR
This study reveals that age, GGT, and albumin are clinical factors influencing LSM values, which reinforces the need to interpret L SM values in the context of a defined diagnosis, biochemical data, radiologic examination, and other clinical findings.
The Association between Liver Fibrosis Measurement by Transient Elastography and Liver Biopsy in Chronic Hepatitis B Patients
TLDR
Liver stiffness measured by TE has an acceptable correlation with histological liver fibrosis in patients with chronic hepatitis B (CHB) patients.
[Changes in liver stiffness after acute or chronic liver injury due to viral hepatitis--does fibrosis exist after recovery from acute viral hepatitis?].
  • J. H. Kim, H. Yim, +13 authors H. Ryu
  • Medicine, Biology
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • 2009
TLDR
The data suggest that liver fibrosis is a long-term sequela of chronic hepatitis, and not developed in patients who recovered from acute viral hepatitis.
Circulating markers of liver fibrosis progression.
Clinical application of liver stiffness measurement using transient elastography in chronic liver disease from longitudinal perspectives.
TLDR
Extended applications of transient TE in prediction of the development of real clinical endpoints from a longitudinal perspective are discussed, under the concept in which the clinical course of liver fibrosis is dynamic and bidirectional, especially when appropriate intervention is commenced.
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References

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TLDR
The diagnostic accuracy of measuring the liver stiffness in addition to measuring the other biochemical markers such as the aspartate transaminase to platelet ratio index [APRI] and the AST/ALT ratio was assessed.
Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C
TLDR
Noninvasive assessment of liver stiffness with transient elastography appears as a reliable tool to detect significant fibrosis or cirrhosis in patients with chronic hepatitis C.
Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study
TLDR
Transient elastography is a promising non-invasive method for detection of cirrhosis in patients with chronic liver disease and its use for the follow up and management of these patients could be of great interest and should be evaluated further.
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TLDR
Fibroscan is a reliable method for the diagnosis of Cirrhosis in patients with chronic liver diseases, better at excluding than at predicting cirrhosis using a threshold of 14.6 kPa, and false‐negatives are mainly attributable to inactive or macronodular cirrhoses.
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TLDR
Liver stiffness is a good method for the evaluation of liver fibrosis that is feasible in more than 95% of patients and other non-invasive methods such as biochemical methods or liver biopsy could therefore be used only in patients with failure of FibroScan examination.
Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.
TLDR
FibroScan is a simple and effective method for assessing liver fibrosis, with similar performance to FibroTest and APRI, and could avoid a biopsy procedure in most patients with chronic hepatitis C.
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TLDR
Sampling variability exists on percutaneous liver biopsy in patients with chronic HCV infection and should be taken into consideration when decisions regarding prognosis and therapy are made based on biopsy, and when defining histological response to antiviral regimens.
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