[Liver growth factor improves pulmonary fibrosis secondary to cadmium administration in rats].

@article{MartnezGaln2010LiverGF,
  title={[Liver growth factor improves pulmonary fibrosis secondary to cadmium administration in rats].},
  author={Lourdes Mart{\'i}nez-Gal{\'a}n and Laura del Puerto-Nevado and Sandra P{\'e}rez-Rial and Juan Jos{\'e} D{\'i}az-Gil and Nicol{\'a}s Gonz{\'a}lez-Mangado and Germ{\'a}n Peces-Barba},
  journal={Archivos de bronconeumologia},
  year={2010},
  volume={46 1},
  pages={20-6}
}
INTRODUCTION Liver growth factor (LGF) is a liver mitogen with regenerating and anti-fibrotic activity even at extrahepatic sites. We used LGF in a lung fibrosis model induced by cadmium chloride (CdCl(2)), to study its antifibrotic capacity. METHODS Forty-two male Wistar rats were administered a single dose of 0.5ml/rat of CdCl2 0.025% (n=21) or the same volume of saline (control group, n=21). After 35 days, once a lesion was established, we started a 3 week treatment with LGF, after which… CONTINUE READING