[Liver damage caused by psychopharmaceuticals].

  title={[Liver damage caused by psychopharmaceuticals].},
  author={Emanuele Altomare and Gianluigi Vendemiale and V Procacci and A P Giovine and N Di Reda and O. Albano},
  journal={La Clinica terapeutica},
  volume={131 4},
Liver plays a central role in drug metabolism, particularly in uptake, biotransformation and excretion of metabolites. Among these metabolic steps biotransformation represents the most critical factor in drug-induced liver damage, especially when hepatic protective mechanisms, such as the tripeptide glutathione (GSH), are decreased thereby predisposing to… CONTINUE READING