[Ligands of RAGE-Proteins: Role in Intercellular Communication and Pathogenesis of Inflammation].

@article{Uspenskaya2015LigandsOR,
  title={[Ligands of RAGE-Proteins: Role in Intercellular Communication and Pathogenesis of Inflammation].},
  author={Yu A Uspenskaya and Yu K Komleva and Elena Pozhilenkova and Vladimir Salmin and Olga L. Lopatina and Andriy Fursov and P V Lavrentiev and Olga A Belova and Alla Salmina},
  journal={Vestnik Rossiiskoi akademii meditsinskikh nauk},
  year={2015},
  volume={6},
  pages={
          694-703
        }
}
The review contains data on the diversity of endogenous ligands of RAGE receptors (receptor for advanced glycation end products) that play an important role in the signal transduction in (patho) physiological conditions. RAGE takes part in various physiological processes like cell growth and survival, apoptosis and regeneration. They serve as regulators of inflammatory reactions due to their ability to induce secretion of cytokines and chemokines. In addition, they facilitate elimination of… CONTINUE READING