Corpus ID: 12413592

[Lidocaine as an immunomodulator in a toxic liver lesion].

@article{Uteshev1997LidocaineAA,
  title={[Lidocaine as an immunomodulator in a toxic liver lesion].},
  author={B. S. Uteshev and L. Prokopenko and E. N. Konoplia},
  journal={Eksperimental'naia i klinicheskaia farmakologiia},
  year={1997},
  volume={60 2},
  pages={
          45-8
        }
}
  • B. S. Uteshev, L. Prokopenko, E. N. Konoplia
  • Published 1997
  • Medicine
  • Eksperimental'naia i klinicheskaia farmakologiia
  • D-galactosamine (DGA) increases the malonic dialdehyde (MDA) content in the erythrocytes, reduces the ATP content, and induces the appearance of immunosuppressive properties in the red cells. Administration of lidocaine attenuates or completely removes these effects of DGA in poisoned animals. Extracorporeal treatment of the erythrocytes of intact rats with blood serum of DGA-poisoned reduces the ATP content and induces the appearance of immunosuppressive properties in the erythrocytes. Blood… CONTINUE READING