[Levofloxacin adverse effects, data from clinical trials and pharmacovigilance].

  title={[Levofloxacin adverse effects, data from clinical trials and pharmacovigilance].},
  author={Claude Carbon},
  volume={56 1},
With 5388 patients in the marketing application dossiers and post-marketing experience of more than 130 million prescriptions of levofloxacin worldwide, the tolerability profile of this anti-infective is now well defined. During clinical trials, 12 per cent of patients treated with levofloxacin experienced an adverse event considered to be related to the study drug compared with 13 per cent of the patients with a comparator. Nausea and diarrhoea were the most frequent adverse effects. During… CONTINUE READING