[Leu5]enkephalin: four cocrystallizing conformers with extended backbones that form an antiparallel β-sheet

@article{Karle1983Leu5enkephalinFC,
  title={[Leu5]enkephalin: four cocrystallizing conformers with extended backbones that form an antiparallel $\beta$-sheet},
  author={I. Karle and J. Karle and D. Mastropaolo and A. Camerman and N. Camerman},
  journal={Acta Crystallographica Section B-structural Science},
  year={1983},
  volume={39},
  pages={625-637}
}
[LeuS]enkephalin (Tyr-Gly-Gly-Phe-Leu) grown from N,N-dimethylformamide(DMFA)/water crystallizes with four quite different conformers side-by-side in the asymmetric unit. The four conformers with extended backbones form an infinite antiparallel fl-sheet. ]]-sheets related by the twofold screw axis are separated by a 12/~ spacing. Side groups protrude above and below the fl-sheets and are entirely immersed in a thick layer of solvent occupying the volume between fl-sheets. The crystal, stable… Expand

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