[Learning toxicology from carbon tetrachloride-induced hepatotoxicity].

  title={[Learning toxicology from carbon tetrachloride-induced hepatotoxicity].},
  author={Yasusuke Masuda},
  journal={Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan},
  volume={126 10},
  • Yasusuke Masuda
  • Published 2006 in
    Yakugaku zasshi : Journal of the Pharmaceutical…
The mechanism of carbon tetrachloride (CCl4)-induced hepatotoxicity, especially necrosis and fatty liver, has long been a challenging subject of many researchers from various fields over the past 50 years. Even though the mechanisms of tissue damages are different among chemicals and affected tissues, CCl4 has played a role as a key substance of tissue injury. A number of studies have been conducted and various hypotheses have been raised. As a result, several important basic mechanisms of… CONTINUE READING


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