[Latent TGFbeta1 activation in the lung irradiated in vivo].

  title={[Latent TGFbeta1 activation in the lung irradiated in vivo].},
  author={Marcos Duarte Mattos and Edna T. Kimura and Maria Regina R{\'e}gis Silva and Mizue Imoto Egami and Roberto Ara{\'u}jo Segreto and Helena Regina C{\^o}modo Segreto},
  journal={Revista da Associacao Medica Brasileira},
  volume={48 4},
PURPOSE assess the latent and active TGFb1 localization in the lung, whether or not radiation induces latent TGFbeta1 activation, and the distribution of collagen fibers in the irradiated lung. METHODS Thirty two C57BL mice were randomly assigned in two groups: GI (non irradiated animals) and GII (irradiated animals). The mice from GII received a single whole - body radiation dose of 7Gy, using a 60Co source at a dose rate of 0.97 Gy/min. They were sacrificed by cervical dislocation at 1, 14… CONTINUE READING