[LMP1 gene variants of Epstein-Barr virus in patients with some lymphoproliferative malignancies].

@article{Gurtsevich2006LMP1GV,
  title={[LMP1 gene variants of Epstein-Barr virus in patients with some lymphoproliferative malignancies].},
  author={V. E. Gurtsevich and E. V. Goncharova and L. N. Shcherbak and A. M. Kovrigina and Natalia A. Falaleeva and L S Iakovleva and V. N. Stepina and Aneta Popova and A A Sterlikova and Evgenii A Osmanov and Oleg A Pavlish},
  journal={Voprosy virusologii},
  year={2006},
  volume={51 2},
  pages={35-9}
}
The samples of tumor biopsy, blood, and saliva from 10 patients with Hodgkin's disease, 10 patients with non-Hodgkin's lymphoma, and the blood samples of 20 donors were tested by polymerase chain reaction (PCR) for standard (wild) B95-8 and Cao-like (deleted) variants of the LMP1 gene. The paraffin sections of most PCR-tested tumors were also investigated by immunohistochemistry using the monoclonal antibodies S12 or 7D7 to detect the expression of the standard or Cao-like variants of LMP1… CONTINUE READING