[LH and GnRH antagonists].

  title={[LH and GnRH antagonists].},
  author={François Olivennes},
  journal={Journal de gynecologie, obstetrique et biologie de la reproduction},
  volume={31 2 Pt 2},
New GnRH antagonists are available in clinical practice. The different studies have confirmed the efficacy of these antagonists in preventing the LH surge. Two protocols have been described: in the multiple dose regimens, small doses of antagonist (0.25 mg) are injected starting on stimulation day 5 or 6 until hCG. In the single dose protocol, one injection of a larger dose (3 mg) is proposed in the late follicular phase. The remaining levels of endogenous LH appears to be sufficient in the… CONTINUE READING