[Ki67 and p53 in laryngeal epithelial lesions: correlations with risk factors].

@article{Leopardi2001Ki67AP,
  title={[Ki67 and p53 in laryngeal epithelial lesions: correlations with risk factors].},
  author={Giuliana Leopardi and Gianluca Serafini and Costantino Simoncelli and Vienna Ludovini and Lorenza Pistola and G Altissimi},
  journal={Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale},
  year={2001},
  volume={21 4},
  pages={243-7}
}
Laryngeal carcinoma-the prototype of epithelial tumors in the head and neck region-has been the greatest source of information on the biological behavior of such neoplasms. Many Authors have suggested that smoke, and to a lesser extent alcohol, play a role in the genesis of this carcinoma although the exact biological mechanism for such involvement is still not clear. The present study analyzed two important biological indicators (p53 and Ki67) in benign and malignant epithelial lesions of the… CONTINUE READING