[KIL-d] Protein Element Confers Antiviral Activity via Catastrophic Viral Mutagenesis.

@article{Suzuki2015KILdPE,
  title={[KIL-d] Protein Element Confers Antiviral Activity via Catastrophic Viral Mutagenesis.},
  author={Genjiro Suzuki and Jonathan S. Weissman and Motomasa Tanaka},
  journal={Molecular cell},
  year={2015},
  volume={60 4},
  pages={651-60}
}
Eukaryotic cells are targeted by pathogenic viruses and have developed cell defense mechanisms against viral infection. In yeast, the cellular extrachromosomal genetic element [KIL-d] alters killer activity of M double-stranded RNA killer virus and confers cell resistance against the killer virus. However, its underlying mechanism and the molecular nature… CONTINUE READING