[Isolation of blood caffeine as a model substance by enzymatic hydrolysis].

@article{Strelova2008IsolationOB,
  title={[Isolation of blood caffeine as a model substance by enzymatic hydrolysis].},
  author={O Iu Strelova and N A Chuvina},
  journal={Sudebno-meditsinskaia ekspertiza},
  year={2008},
  volume={51 4},
  pages={28-31}
}
Organic solvent extraction of toxic compounds from blood either directly or following precipitation of serum proteins yields only free fractions. It is proposed to dissociate toxin-protein complexes in blood samples by enzymatic hydrolysis. Model caffeine complexes in an albumin solution were treated by tripsin, chemotripsin, and papain. The best results… CONTINUE READING