[Irisin--a new mediator of energy homeostasis].

  title={[Irisin--a new mediator of energy homeostasis].},
  author={Katarzyna Pukajło and Katarzyna Kolackov and Łukasz Łaczmański and Jacek Daroszewski},
  journal={Postepy higieny i medycyny doswiadczalnej},
Skeletal muscles as an active hormonal compartment in the response of physical activity secrete substances named myokines capable of modulating metabolic processes. Myokines take part in communication between muscles and other tissues. Irisin (Ir) - a newly discovered adipomyokine - is cleaved and secreted to the circulation from a fibronectin type III domain containing protein 5 (FNDC5). The mechanism of Ir action has not been described precisely, and receptors for the molecule are not defined… CONTINUE READING