[Irinotecan pharmacogenetics in Japanese cancer patients: roles of UGT1A1*6 and *28].

@article{Sai2008IrinotecanPI,
  title={[Irinotecan pharmacogenetics in Japanese cancer patients: roles of UGT1A1*6 and *28].},
  author={K. P. Preethi Manohari Sai and Jun-ichi Sawada and Hironobu Minami},
  journal={Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan},
  year={2008},
  volume={128 4},
  pages={575-84}
}
Recent progress in pharmacogenetic research has made "personalized medicine" a reality, where a suitable drug at the appropriate dosage is prescribed based on individual genetic factors. Irinotecan, an anticancer drug, is one of the models for personalized medicine, and a number of clinical studies have revealed significant associations between UGT1A1(*)28… CONTINUE READING