Corpus ID: 39512820

[Involvement of the thalamic-cortical-striatal circuit in patients with obsessive-compulsive disorder during an inhibitory control task with reward and punishment contingencies].

@article{PenaGarijo2011InvolvementOT,
  title={[Involvement of the thalamic-cortical-striatal circuit in patients with obsessive-compulsive disorder during an inhibitory control task with reward and punishment contingencies].},
  author={Josep Pena-Garijo and A. Barr{\'o}s-Loscertales and N. Ventura-Campos and M. {\'A}. Ruip{\'e}rez-Rodr{\'i}guez and S. Edo-Villamon and C. {\'A}vila},
  journal={Revista de neurologia},
  year={2011},
  volume={53 2},
  pages={
          77-86
        }
}
INTRODUCTION Recent neuroimaging studies conducted on obsessive-compulsive disorder (OCD) show alterations in the fronto-thalamic-striatal circuit, which would give rise to an executive dysfunction. This could be the neurocognitive substrate underlying the main symptoms of OCD, i.e. obsessions and compulsions. SUBJECTS AND METHODS Both brain activity and behavioural performance of a group of 13 patients with OCD were compared with a control group of 13 healthy subjects by means of functional… Expand
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