[Involvement of protein kinase C in the acid secretion of gastric parietal cells].

@article{Choquet1991InvolvementOP,
  title={[Involvement of protein kinase C in the acid secretion of gastric parietal cells].},
  author={Armelle Choquet and Richard Magous and Jean Pierre Bali},
  journal={Comptes rendus des seances de la Societe de biologie et de ses filiales},
  year={1991},
  volume={185 5},
  pages={357-69}
}
In isolated parietal cells from gastric fundic mucosa of the rabbit, activation of protein kinase C by the stable diacylglycerol analogue, OAG, and by the phorbol ester, TPA, inhibited in a dose-dependant manner both histamine-stimulated AP accumulation (EC50: 25 microM and 1.6 nM, respectively) and carbachol-stimulated AP accumulation (EC50: 15 microM and… CONTINUE READING