[Intratympanic drug delivery for the treatment of inner ear diseases].

  title={[Intratympanic drug delivery for the treatment of inner ear diseases].},
  author={C. Ilia Herr{\'a}iz and Jos{\'e} Miguel Aparicio and Guillermo Plaza},
  journal={Acta otorrinolaringologica espanola},
  volume={61 3},
INTRODUCTION Intratympanic drug delivery for labyrinth diseases is a non-aggressive outpatient procedure where drugs reach high concentrations in the cochlea and minimum systemic diffusion. The aim of this review is to update the delivery techniques and report on the results obtained with different substances in cochleovestibular disorders. New perspectives in drug development and gene therapy are discussed. MATERIAL AND METHOD We have analyzed the literature published to date using the… CONTINUE READING