[Internalization of antibody-targeted immunonanoparticles into human hepatoma cells and its reversal effect on MDR].


OBJECTIVE To observe if antibody-targeted immunonanoparticles could internalize into sensitive and multidrug resistance (MDR) cells of human hepatoma; and to study if the immunonanoparticles could reverse the MDR. METHODS Human hepatoma-specific adriamycin-loaded human serum albumin immunonanoparticles (HAb18-ADR-HSA-NP) were incubated with human hepatoma… (More)