[Interactions of intravenous anesthetics with cerebral alpha-2-adrenoceptors].


OBJECTIVE Up to date the exact mechanisms of action of anaesthetics on structures of the central nervous system have not been elucidated. Agents acting on central alpha 2-adrenoceptors have been demonstrated to possess potent sedative properties. Beside the classical agonists, general anaesthetics that are currently in clinical use e.g. etomidate have also… (More)


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