[Interaction of thyroid hormones with immunoglobulins isolated from human blood serum. II. Structural elements and localization of thyroxine-binding segment in the immunoglobulin M molecule].

Abstract

The structural characteristics and topography of the thyroxine T4-binding site on the human immunoglobulin M (IgM) molecule have been studied using affinity binding with T4 structural analogs blocking the formation of the T4-IgM complex with proteins displaying an affinity for individual structural components of IgM and proteolytic fragmentation followed by… (More)

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