[Interaction of alkali metal ions with Ca2+-binding center of Ca2+- ATPase of the sarcoplasmic reticulum in skeletal muscles].

@article{Timonin1989InteractionOA,
  title={[Interaction of alkali metal ions with Ca2+-binding center of Ca2+- ATPase of the sarcoplasmic reticulum in skeletal muscles].},
  author={I M Timonin and S N Dvoriantsev and Valery V. Petrov and Enno K Ruuge and D. O. Levitskii},
  journal={Biokhimiia},
  year={1989},
  volume={54 7},
  pages={1170-8}
}
Sodium ion interaction with sarcoplasmic reticulum (SR) membranes leads to considerable alterations of the [23Na]NMR lineshape. Na+ binding to SR in the presence of Ca2+ and H+ is well described by a model which postulates a competitive ion binding to high and low affinity sites of Ca2+-ATPase. The dissociation constant, Kd, for high and low affinity sites… CONTINUE READING