[Inhibitory effects of the extract of pilose antler on monoamine oxidase in aged mice].

@article{Chen1992InhibitoryEO,
  title={[Inhibitory effects of the extract of pilose antler on monoamine oxidase in aged mice].},
  author={Xiaoguang Chen and Ying Jia and Ben Xiang Wang},
  journal={Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica},
  year={1992},
  volume={17 2},
  pages={107-10, 128}
}
It was demonstrated that the water extract of Pilose Antler (WEPA) showed a higher inhibitory effect on MAO-B activities in the liver and brain tissues of aged mice, but nearly no effect on NAO-A. WEPA could significantly increase the contents of 5-HT, NE and DA in the brain tissues of aged mice. In vitro experiments revealed that the inhibition of WEPA on MAO-B was competitive, but on MAO-A was of mixed-type.