[Inhibitory effect of monoclonal antibody PD4 on Ha-ras transformed cells Rat3-3].

  • Wen-ke Yin
  • Published 1991 in
    Zhonghua zhong liu za zhi [Chinese journal of…


McAbPD4 could inhibit the proliferation of transformed cells Rat3-3 with an inhibition rate of 72.3% in vitro. Moreover, McAbPD4 decreased the Rat3-3's colony forming ability on soft agar and tumorigenicity in nude mice. By Flow Cytometry, it was indicated that the inhibitory effect was due to a blockade between G1 and S phase. It was shown by Western… (More)