[Inhibitory effect of hydrogen sulfide on cardiac fibroblast proliferation].

  title={[Inhibitory effect of hydrogen sulfide on cardiac fibroblast proliferation].},
  author={Jun Liu and D. Hao and Yi-Chun Zhu},
  journal={Sheng li xue bao : [Acta physiologica Sinica]},
  volume={63 4},
The aim of the present study was to investigate the role of hydrogen sulfide (H(2)S) in the proliferation of neonatal rat cardiac fibroblasts (NRCFs). Proliferation of NRCFs was induced by the presence of fetal bovine serum (FBS) or angiotensin II (Ang II) at various concentrations. The concentration-dependent effect of NaHS (donor of H(2)S) on NRCFs proliferation was examined. NRCFs proliferation was assessed by 5'-bromo-2'-deoxyuridine (BrdU) incorporation method. Reactive oxygen species (ROS… CONTINUE READING


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