[Inhibition of the free, biologically active testosterone level by Turisteron in patients with prostate cancer].
@article{Stahl1987InhibitionOT, title={[Inhibition of the free, biologically active testosterone level by Turisteron in patients with prostate cancer].}, author={F. Stahl and D. Schnorr and W. Rohde and G. D{\"o}rner}, journal={Zeitschrift fur Urologie und Nephrologie}, year={1987}, volume={80 3}, pages={ 135-8 } }
Apart from their antigonadotropic effect oestrogens also directly inhibit the androgen secretion of the testicles. Thus, on the 20th day of treatment the LH-level after 12 g diethylstilbestrol diphosphate (DSDP) decreases only to approximately 50% of the initial value, while the whole testosterone (T), however, is reduced to less than 5%. The sexual hormone binding globulin is significantly more increased (p less than 0.001) by the estrogen treatment than after orchidectomy only. Therefore, the… Expand