Corpus ID: 30221813

[Inhibition of gastric acid secretion by vascularly perfused secretin and somatostatin in isolated rat stomach].

@article{Wang1989InhibitionOG,
  title={[Inhibition of gastric acid secretion by vascularly perfused secretin and somatostatin in isolated rat stomach].},
  author={L. D. Wang and L. Zhou},
  journal={Sheng li xue bao : [Acta physiologica Sinica]},
  year={1989},
  volume={41 6},
  pages={
          575-82
        }
}
  • L. D. Wang, L. Zhou
  • Published 1989
  • Chemistry, Medicine
  • Sheng li xue bao : [Acta physiologica Sinica]
Effects of secretin and somatostatin on acid secretion and its relation to prostaglandin E, I2 release in the totally isolated vascularly perfused rat stomach were studied. The results showed: (1) Secretin and somatostatin both markedly inhibited acid secretion stimulated by pentagastrin. Indomethacin could reverse the inhibitory effects of acid secretion by secretin and somatostatin. (2) Secretin increased PGE and PGI2 metabolite 6-Keto-PGF1 alpha release significantly. Somatostatin only… Expand