[Inhibition of airway mucous hypersecretion by azithromycin through matrix metalloproteinase 9].

OBJECTIVE To investigate the mechanism of azithromycin (AZT) inhibiting the airway mucous hypersecretion through matrix metalloproteinase 9 (MMP9). METHODS After culturing, the airway epithelial cells of line HBE16 were stimulated with neutrophil elastase (NE) and pretreated with AZT and epidermal growth factor receptor (EGFR) antagonist BIBX1522. Then… CONTINUE READING