[Inhibition of HCV IRES controlled reporter gene expression by RNA interference].

Abstract

OBJECTIVE To develop a RNAi approach that specifically targets the HCV IRES sequence by vector-expressed short hairpin RNA (shRNA) in vitro, and to assess the inhibitory effect of the shRNA on reporter gene expression. METHODS Eukaryotic expressing plasmids, pIRES-GFP and p5' UTR-Luc containing GFP or luciferase gene controlled by HCV IRES were… (More)

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Cite this paper

@article{Chen2006InhibitionOH, title={[Inhibition of HCV IRES controlled reporter gene expression by RNA interference].}, author={Wei-Xian Chen and Lin-na Shan and Juan Chen and Zhen-zhen Zhang and Bing-qiang Zhang and Ailong Huang}, journal={Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology}, year={2006}, volume={14 7}, pages={521-4} }