[Inhibition by SKF38393 of GABA-activated currents in rat DRG neurons].

@article{Li1998InhibitionBS,
  title={[Inhibition by SKF38393 of GABA-activated currents in rat DRG neurons].},
  author={Qingyu Li and Qi-wei Wang and Zhi Wang Li},
  journal={Sheng li xue bao : [Acta physiologica Sinica]},
  year={1998},
  volume={50 3},
  pages={280-8}
}
Experiments were performed on neurons freshly isolated from rat DRG using whole-cell patch-clamp techniques. The majority of the neurons examined were sensitive to GABA (60/70) in the concentration range from 10(-6) to 10(-3) mol/L, showing obvious desensitization. In the 60 GABA-sensitive cells, responses induced by selective agonist of dopamine D1 receptor SKF38393 [(+/-) SKF38393HCL] manifested three types: (1) outward current (7/60); (2) inward current (5/60) and (3) no detectable response… CONTINUE READING