[Influence of sexual difference on expression of Toll-like receptor 4 and myeloid differential protein-2 mRNA in the lung in septic rats].

OBJECTIVE To investigate the influence of gender on the gene expression of Toll-like receptor 4 (TLR4), myeloid differential protein-2 (MD-2) and tumor necrosis factor-alpha (TNF-alpha) in the lung in septic rats. METHODS The total RNA from normal and lipopolysaccharide (LPS)-challenged rats was extracted by Trizol reagent. The gene expressions of TLR4… (More)