Corpus ID: 44570393

[Influence of changes in the state of brain neurotransmitter and peptidergic systems on circadian rhythms and behavior of rats].

@article{Kravchenko2012InfluenceOC,
  title={[Influence of changes in the state of brain neurotransmitter and peptidergic systems on circadian rhythms and behavior of rats].},
  author={E. Kravchenko and L. M. Ol'gomets},
  journal={Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova},
  year={2012},
  volume={62 4},
  pages={
          453-64
        }
}
The influence of changes in the state of a number of neurotransmitter and peptidergic brain systems on the circadian rhythms and behaviour of rats was studied. Prolylleucine (oxytocine dipeptide fragment) eliminates disorders of circadian motility rhythm in SHR rats induced by "injection" stress, impedes dysrhythmias caused by application of cholinergic and glutamatergic modulators in SHR and WKY rats, and prevents cognitive disorders in SHR rats produced by REM sleep deprivation.