[Influence of G308A polymorphism of tumor necrosis factor alpha gene on insulin resistance in obese patients after weight loss].

@article{Luis2007InfluenceOG,
  title={[Influence of G308A polymorphism of tumor necrosis factor alpha gene on insulin resistance in obese patients after weight loss].},
  author={Danielv Antonio de Luis and Roc{\'i}o Aller and Olazt Izaola and Manuel Gonz{\'a}lez Sagrado and R. Gonz{\'a}lez Conde and E. Kyle Romero},
  journal={Medicina clinica},
  year={2007},
  volume={129 11},
  pages={401-4}
}
BACKGROUND AND OBJECTIVE An accumulating body of evidence shows that modest weight loss (5%) through dietary changes and exercices is an effective means for managing obesity-associated disorders. As far as we kow, nobody has described the dietary response in insulin resistance and adipocytokines, analyzing the G308A variant of the tumor necrosis factor alpha (TNF-alpha) gene. The aim of our study was to investigate the influence of G308A polymorphism in the TNF-alpha gene on insulin resistance… CONTINUE READING
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