[Influence of 4-methylesculetol on the response of segments of isolated coronary arteries to adrenaline, in presence of pyrogallol].


The adrenaline (AD) induced relaxation in the smooth muscle is increased by bioflavonoids, possibly via cathecol-0-methyltransferase (COMT) inhibition. In order to test this hypothesis, we studied the influence of 4-methylesculetin (4-Me), alone or associated with ascorbic acid, on the response of isolated coronary strips to AD, in the presence of… (More)


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