[Induction of ecto-5'-nucleotidase of rat mesangial cells in culture].

It is very well known that macrophages via their secretory products act on many mesangial cell activities. IL-1b (interleukin-1b), tumor necrosis factor alfa (TNF-a) and prostoglandin E2 (PGE2) effect on rat mesangial cell ecto-enzymes: ecto-5'-nucleotidase and ecto-Mg++-ATP-ase were investigated. Ecto-5'-nucleotidase activity was increased in a dose… CONTINUE READING