Corpus ID: 21250522

[Induction of differentiation of human promyelocytic leukemia (HL-60) cells by new retinoid R-81001].

@article{Jiao1989InductionOD,
  title={[Induction of differentiation of human promyelocytic leukemia (HL-60) cells by new retinoid R-81001].},
  author={L. Jiao},
  journal={Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae},
  year={1989},
  volume={11 2},
  pages={
          102-6
        }
}
  • L. Jiao
  • Published 1989
  • Biology, Medicine
  • Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
By using soft agar colony-forming assay, a monoclonal subline of human promyelocytic leukemia HL-60 cells was isolated and inducing activity of differentiation of a new retinoid R-81001 on the cells was studied. Phenotypic changes, such as biologic behavior, morphological and biochemical characteristics, show that R-81001 can induce HL-60 cells to differentiate along the myeloid pathway.