[Induction of cell differentiation and development of new anticancer drugs].

  title={[Induction of cell differentiation and development of new anticancer drugs].},
  author={Noriko Takahashi},
  journal={Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan},
  volume={122 8},
  • N. Takahashi
  • Published 1 August 2002
  • Biology, Chemistry
  • Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Cell differentiation is essential for normal growth and homeostasis, and drug-induced differentiation of tumor cells into benign or normal cells is an important approach for anticancer chemotherapy. Studies of induction mechanisms for cell differentiation and discovery of differentiation-inducing factors are thus critical components of drug development. The Screening of differentiation-inducing factors, such as purified aldehyde reductase, a xenobiotic metabolite enzyme, that induces… 

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