[Increased prevalence of APC-resistance (factor V Leiden mutation) in patients with postthrombotic syndrome].

@article{Gaber2000IncreasedPO,
  title={[Increased prevalence of APC-resistance (factor V Leiden mutation) in patients with postthrombotic syndrome].},
  author={Yvonne Gaber and H. Siemens and Wilfried Schmeller},
  journal={Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete},
  year={2000},
  volume={51 8},
  pages={590-2}
}
BACKGROUND AND OBJECTIVE APC resistance (Factor V Leiden mutation) is the most often diagnosed hereditary thrombolytic defect. Data about the prevalence in patients with leg ulcers, especially postthrombosis, are limited of this defect. PATIENTS/METHODS APC resistance was determined in 100 patients with venous leg ulcers. 53 patients had ulcers caused by postthrombotic syndrome and 47 patients ulcers associated with primary varicosities. A control group of 96 healthy volunteers was also… CONTINUE READING