[Increased plasma levels of endothelin in patints with essential arterial hypertension].

@article{Amoroso1996IncreasedPL,
  title={[Increased plasma levels of endothelin in patints with essential arterial hypertension].},
  author={Antonio Amoroso and Marco Cossu and Andra Mariotti and Francesca Guido and Gianni M Ferri and Francesco Giuseppe de Rosa and Giuseppe Sportelli},
  journal={Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques},
  year={1996},
  volume={18 1},
  pages={33-7}
}
Endothelin-1 (ET-1) is an endothelium-derived vasoconstrictive peptide. In this study the Authors measured in 25 subjects (15 with essential hypertension and 10 normal) plasma levels of endothelin-1. Patients with hypertension had significantly higher plasma ET-1 concentration than normal subjects (2.18 +/- 1.07 vs. 1.36 +/- 0.40 pg/ml, p < 0.02). Plasma arginine vasopressin, renin activity and aldosterone concentration did not show significant differences between hypertensive and normotensive… CONTINUE READING