[In vivo distributions of 111In and/or 3H labeled lymphocyte in C3H/He mouse (author's transl)].

@article{Shibata1979InVD,
  title={[In vivo distributions of 111In and/or 3H labeled lymphocyte in C3H/He mouse (author's transl)].},
  author={Chieko Shibata and Yoshitomo Shiwaku and Y Ohizumi and Hiroshi Maezawa and Y Okumura and Y Suzuki and K Tsuji and T. Mori},
  journal={Radioisotopes},
  year={1979},
  volume={28 7},
  pages={
          431-6
        }
}
Although 99mTc and 51Cr have been used for lymphocyte labeling, these radionuclides have several disadvantages for study on immunological behaviour of lymphocyte; very high rate elution and low labeling efficiency for both radionuclides, and short half life for 99mTc. Indium-111 has quite suitable physical properties for clinical nuclear medicine, i.e. desirable photon energy (247,173 keV) and 2.8 day half life. 111In-oxine is lipid soluble and is known to pass through the cell membrane and… Expand
1 Citations
[131I]FIAU labeling of genetically transduced, tumor-reactive lymphocytes: cell-level dosimetry and dose-dependent toxicity
TLDR
At median nuclear absorbed doses up to 830 cGy, a 51Cr-release assay against BLCLs showed no loss of immune cytotoxicity, thus demonstrating the functional integrity of genetically transduced, tumor-reactive T cells labeled at this dose level for in vivo cell trafficking and tumor targeting studies. Expand