[Immunology in the severely injured].

  title={[Immunology in the severely injured].},
  author={Eugen Faist and Matthias W. Wichmann},
  journal={Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen},
  volume={68 11},
Immunological complications frequently occur during the clinical course in patients with multiple injuries. The increased release of pro-inflammatory mediators during the immunological response to trauma may lead to the systemic inflammatory response syndrome (SIRS) and furthermore, to multisystem organ failure (MOF), which is associated with a mortality of up to 80%. The development of multiple organ failure following major trauma is associated with remote organ failure, the dysfunction of… CONTINUE READING