[Immunological classification of acute lymphoblastic leukemias (ALL) in childhood. Origin and clinical significance of phenotypic variability].

@article{Thoene1982ImmunologicalCO,
  title={[Immunological classification of acute lymphoblastic leukemias (ALL) in childhood. Origin and clinical significance of phenotypic variability].},
  author={I Thoene and Hartmut Kabisch and James D. Mueller and Kurt Winkler and G{\"u}nther Landbeck},
  journal={Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde},
  year={1982},
  volume={130 12},
  pages={883-90}
}
Leucemic cells in 54 children with ALL have been typed immunologically by conventional antisera, monoclonal antibodies and receptor tests as c-ALL (62.5%), T-ALL/NHL (18.5%), B-ALL (1.9%) and AUL (16.6%), respectively. The different subtypes showed a noteworthy heterogeneity in receptor patterns which may reflect an arrest in discrete differentiation stages within the maturation pathway of a lymphoid cell population. The characteristic set of clinical symptoms of T-cell neoplasias could once… CONTINUE READING

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Of interest is a clear trend for a less favourable outcome in AUL as compared to c - ALL and in NHL versus ALL as a whole , whereas no difference could be found between T - ALL and non T - ALL during therapy .
Of interest is a clear trend for a less favourable outcome in AUL as compared to c - ALL and in NHL versus ALL as a whole , whereas no difference could be found between T - ALL and non T - ALL during therapy .
Of interest is a clear trend for a less favourable outcome in AUL as compared to c - ALL and in NHL versus ALL as a whole , whereas no difference could be found between T - ALL and non T - ALL during therapy .
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