Corpus ID: 32664866

[Immunogenicity of recombinant Lactobacillus casei expressing VP2 protein of infectious bursal disease virus in chickens].

@article{Lin2014ImmunogenicityOR,
  title={[Immunogenicity of recombinant Lactobacillus casei expressing VP2 protein of infectious bursal disease virus in chickens].},
  author={H. Lin and S-M Hou and S. Wang and Yupeng Wang and Yunyan LuanI and X. Hou},
  journal={Sheng wu gong cheng xue bao = Chinese journal of biotechnology},
  year={2014},
  volume={30 11},
  pages={
          1679-90
        }
}
  • H. Lin, S-M Hou, +3 authors X. Hou
  • Published 2014
  • Biology, Medicine
  • Sheng wu gong cheng xue bao = Chinese journal of biotechnology
In order to determine immunogenicity and protective effect in chickens, we used the IBDV (Infectious bursal disease virus)-Vp2/Lactobacillus casei as antigen transfer system. First, the immunized and control chickens were challenged by IBDV/DQ at lethal dose to determine the protective ratio. Second, chickens were orallyand intranasally vaccinated twice with 10(9) CFU/mL pLA-VP2/L. casei, pLA/L. casei and PBS as negativecontrol and commercial vaccine as positive control. The bursa injury and… Expand
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References

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